Best Grey's Anatomy trivia quiz questions

Test your knowledge on the medical drama Grey's Anatomy and its characters, locations, and more.

  • Which Grey's Anatomy character has a photographic memory?

    Lexie Grey
  • Which character did not appear in the first episode of Grey's Anatomy?

    Lexie Grey
  • What is the nickname given to the group of surgical interns at the beginning of the show?

    The Fab Five
  • What is the name of the bar owned by Joe and frequented by the doctors?

    Emerald City Bar
  • What is the name of the head of neurosurgery at Seattle Grace Hospital?

    Dr. Derek Shepherd
  • What is the name of Izzie Stevens' high school boyfriend who comes to Seattle Grace for treatment?

    Hank
  • What is the name of Dr. Callie Torres and Dr. Arizona Robbins' daughter?

    Sofia Robbin Sloan Torres
  • Which character loses their leg in a plane crash?

    Arizona Robbins
  • Which character did Eric Dane play on Grey's Anatomy?

    Dr. Mark Sloan
  • What is the name of the doctor who has a romantic relationship with Cristina Yang?

    Owen Hunt
  • Which character did Justin Chambers play on Grey's Anatomy?

    Dr. Alex Karev
  • Which character did Kate Walsh play on Grey's Anatomy?

    Dr. Addison Montgomery
  • Who is the creator of Grey's Anatomy?

    Shonda Rhimes
  • What is the profession of Meredith Grey's mother, Ellis Grey?

    Surgeon
  • What is the name of the hospital's chief of surgery?

    Dr. Richard Webber
  • What is the name of the medical drama that serves as a spin-off from Grey's Anatomy?

    Private Practice
  • What is the name of the hospital's resident who is known for being a devout Christian?

    Dr. Sydney Heron
  • Which character leaves Grey Sloan Memorial Hospital to work at the Klausman Institute for Medical Research?

    Cristina Yang
  • What is the name of the doctor who has a romantic relationship with Richard Webber?

    Catherine Avery
  • What is the name of the hospital shooter who appears in season six?

    Gary Clark
  • What is the name of the hospital's resident who is known for being a troublemaker?

    Dr. Alex Karev
  • What song plays during the opening credits of Grey's Anatomy?

    Cosy In The Rocket
  • What is the name of the hospital's rival in season ten?

    San Francisco Memorial Hospital
  • Which character did not pass their medical boards in Season 8?

    April Kepner
  • What is the name of the doctor who has a romantic relationship with Callie Torres?

    Arizona Robbins
  • Which character accidentally kills a patient with an adrenaline overdose?

    Sydney Heron
  • Which actor played Dr. Preston Burke?

    Isaiah Washington
  • What is the name of the hospital's resident who is known for being an overachiever?

    Dr. Cristina Yang
  • What is the name of the hospital's resident who is known for being a rebel?

    Dr. April Kepner
  • Who is the only character to have appeared in every season of Grey's Anatomy?

    Miranda Bailey
  • What is the name of the hospital where Grey's Anatomy takes place?

    Grey Sloan Memorial Hospital
  • What is the name of the hospital that replaces Seattle Grace Mercy West in season nine?

    Grey Sloan Memorial Hospital
  • Which character was originally going to be portrayed by Sandra Oh?

    Dr. Miranda Bailey
  • What is the name of the hospital's resident who is known for being a recovering alcoholic?

    Dr. Amelia Shepherd
  • What is the name of the bar that the doctors frequent?

    Joe's Bar
  • What is the name of Dr. Amelia Shepherd's brother?

    Dr. Derek Shepherd
  • What is the name of the hospital's resident who is known for being a former patient?

    Dr. Heather Brooks
  • Which character wins the Harper Avery Award?

    Dr. Cristina Yang
  • Which character accidentally kills a patient by administering the wrong medication?

    Dr. Charles Percy
  • Who is the chief of surgery at Seattle Grace Hospital?

    Richard Webber
  • Which character did actress Kate Walsh portray?

    Addison Montgomery
  • What is the name of the hospital's resident who is known for having a crush on Dr. Derek Shepherd?

    Dr. Rose
  • What is the nickname given to the group of surgical interns in Season 1?

    The Fab Five
  • What is the name of the doctor who has a romantic relationship with Jo Wilson?

    Alex Karev
  • Which character suffers from OCD?

    Dr. Sam Bello
  • Which character leaves Grey Sloan Memorial Hospital to work at the Klausman Institute for Medical Research?

    Dr. Cristina Yang
  • Which character is known for their love of baking?

    Dr. April Kepner
  • What is the name of Dr. April Kepner's first husband?

    Matthew Taylor
  • In which season does Dr. Teddy Altman first appear?

    Season 6
  • What is the name of the doctor who has a romantic relationship with Mark Sloan?

    Julia Canner
  • What is the name of the doctor who has a romantic relationship with Andrew DeLuca?

    Maggie Pierce
  • What is the name of the doctor who has a romantic relationship with Stephanie Edwards?

    Kyle Diaz
  • Which character did Patrick Dempsey play on Grey's Anatomy?

    Dr. Derek Shepherd
  • Who does Meredith Grey have a complicated relationship with throughout the series?

    Derek Shepherd
  • Who is the father of Callie Torres' baby?

    Mark Sloan
  • Which character did Ellen Pompeo play on Grey's Anatomy?

    Dr. Meredith Grey
  • What is the name of the hospital's new orthopedic surgeon in season nine?

    Shane Ross
  • What is the name of the hospital's plastic surgeon who becomes disfigured after a plane crash?

    Dr. Mark Sloan
  • Which character did Sara Ramirez play on Grey's Anatomy?

    Dr. Callie Torres
  • Which actor portrayed Denny Duquette?

    Jeffrey Dean Morgan
  • What is the profession of Dr. Maggie Pierce's biological mother?

    Cardiothoracic Surgeon
  • What is the name of the hospital's resident who is known for being a former model?

    Dr. Izzie Stevens
  • In which season did Lexie Grey first appear on Grey's Anatomy?

    Season 3
  • What is the name of Meredith Grey's dog?

    Doc
  • Which character suffers from dyslexia?

    Dr. Sam Bello
  • What is the name of the doctor who has a romantic relationship with Miranda Bailey?

    Ben Warren
  • Which character did Kevin McKidd play on Grey's Anatomy?

    Dr. Owen Hunt
  • What is the name of the doctor who has a romantic relationship with Addison Montgomery?

    Sam Bennett
  • What is the name of the hospital's cardiothoracic surgeon who dies in season 2?

    Dr. Dylan Young
  • What is the name of the doctor who has a romantic relationship with Leah Murphy?

    Arizona Robbins
  • What is the nickname given to the group of interns that Meredith, Cristina, Alex, and George are a part of?

    The Fab Five
  • Which character did Jesse Williams play on Grey's Anatomy?

    Dr. Jackson Avery
  • What is the name of the doctor who has a romantic relationship with Alex Karev?

    Jo Wilson
  • Who is Meredith Grey's best friend in the show?

    Cristina Yang
  • Which actress plays Dr. Amelia Shepherd on Grey's Anatomy?

    Caterina Scorsone
  • What is the name of the hospital's resident who is known for being a former stripper?

    Dr. Sadie Harris
  • What is the name of the hospital that merges with Seattle Grace in season six?

    Mercy West Medical Center
  • Which character is shot by a gunman during the hospital shooting?

    Dr. Alex Karev
  • Who is the first intern to perform surgery solo?

    George O'Malley
  • Which character dies in a plane crash?

    Dr. Lexie Grey
  • Which character did not appear in the pilot episode?

    Dr. Addison Montgomery
  • In which season does Dr. Mark Sloan make his first appearance?

    Season 2
  • Who becomes the head of pediatric surgery after Arizona Robbins leaves?

    Alex Karev
  • What is the name of the doctor who has a romantic relationship with Maggie Pierce?

    Andrew DeLuca
  • What is the name of the award-winning surgeon who mentors Cristina Yang in Minnesota?

    Dr. Thomas
  • What is the name of the doctor who has a romantic relationship with Nathan Riggs?

    Megan Hunt
  • What is the name of the hospital's resident who is known for being a lesbian?

    Dr. Arizona Robbins
  • What is the name of the hospital in Grey's Anatomy after it is renamed in Season 9?

    Grey Sloan Memorial Hospital
  • What is the name of the doctor who replaces Dr. Preston Burke as head of cardiothoracic surgery?

    Erica Hahn
  • What is the name of the doctor who has a romantic relationship with Teddy Altman?

    Henry Burton
  • Which character is known for baking when they are stressed?

    Miranda Bailey
  • What is the name of the bar frequented by the doctors of Grey's Anatomy?

    Joe's Emerald City Bar
  • Which character becomes Chief of Surgery after Dr. Derek Shepherd?

    Dr. Miranda Bailey
  • What is the name of the hospital's resident who is known for being a former army surgeon?

    Dr. Owen Hunt
  • What is the name of the hospital's resident who is known for being a former homeless teenager?

    Dr. Jo Wilson
  • What year did Grey's Anatomy premiere?

    2005
  • What is the name of the hospital's resident who is known for being a former car thief?

    Dr. Andrew DeLuca
  • Which character has a photographic memory?

    Dr. Shane Ross
  • Which character becomes Chief of Surgery after Dr. Webber?

    Dr. Derek Shepherd
  • What is the name of the hospital's resident who is known for being a survivor of domestic abuse?

    Dr. Jo Wilson
  • Which character dies in the season eleven episode 'How to Save a Life'?

    Derek Shepherd
  • Who is the first surgeon to perform a solo surgery in the show?

    Meredith Grey
  • Which character is revealed to have been married before coming to Seattle Grace?

    Jo Wilson
  • Which character becomes Chief of Surgery after Dr. Richard Webber?

    Dr. Derek Shepherd
  • What is the name of the hospital's resident who is known for being a glasses-wearing nerd?

    Dr. Levi Schmitt
  • What is the name of the plane crash that occurs in season eight?

    Flight 815
  • What is the name of the doctor who has a romantic relationship with Amelia Shepherd?

    Owen Hunt
  • What is the nickname given to the group of interns in Season 1?

    The Fab Five
  • What is the name of the doctor who has a romantic relationship with April Kepner?

    Jackson Avery
  • Which character did Jerrika Hinton play on Grey's Anatomy?

    Dr. Stephanie Edwards
  • What was the original title of Grey's Anatomy during its development?

    Surgeons
  • What medical condition does Dr. Richard Webber suffer from?

    Alcoholism
  • What is the name of the doctor who has a romantic relationship with Arizona Robbins?

    Carina DeLuca
  • Who is the biological father of Callie Torres and Arizona Robbins' daughter?

    Mark Sloan
  • What is the name of Meredith and Derek's dog?

    Doc
  • What is the name of Dr. Richard Webber's wife?

    Adele Webber
  • Which character's father is a famous surgeon?

    Jackson Avery
  • Which character did Isaiah Washington play on Grey's Anatomy?

    Dr. Preston Burke
  • Who is the main character of Grey's Anatomy?

    Meredith Grey
  • Which character did Sandra Oh play on Grey's Anatomy?

    Dr. Cristina Yang
  • Which character did Chyler Leigh portray on Grey's Anatomy?

    Dr. Lexie Grey
  • What is the name of the hospital's resident who is known for being a germaphobe?

    Dr. Miranda Bailey
  • Which character from Grey's Anatomy appeared in all 17 seasons?

    Meredith Grey
  • Which character is revealed to have been married before starting their internship at Seattle Grace?

    Dr. Jo Wilson
  • What is the name of the surgical contest created by Jackson Avery in Season 14?

    The Grey Sloan Surgical Innovation Contest
  • What is the name of the surgical method developed by Dr. Derek Shepherd?

    The Shepherd Method
  • What was the original title of Grey's Anatomy before it was changed?

    Surgeons
  • What is the name of the spin-off series that focuses on Addison Montgomery?

    Private Practice
  • Which character dies in a plane crash in Season 8 finale?

    Dr. Lexie Grey
  • What is the name of the surgical contest introduced in Season 14?

    The Grey Sloan Surgical Innovation Contest
  • Which character is diagnosed with cancer in Season 10?

    Nicole Herman
  • What is the name of the hospital's pediatric surgeon?

    Dr. Arizona Robbins
  • What is the full name of the character played by Sandra Oh?

    Cristina Yang
  • Which character did Kelly McCreary play on Grey's Anatomy?

    Dr. Maggie Pierce
  • What is the name of the hospital's resident who is known for being a former drug addict?

    Dr. Amelia Shepherd
  • Which actor played Denny Duquette on Grey's Anatomy?

    Jeffrey Dean Morgan
  • What is the name of Dr. Izzie Stevens' love interest who dies of a brain tumor?

    Denny Duquette
  • Which character is known for having a dark and twisty personality?

    Dr. Meredith Grey
  • What type of surgery does Dr. Preston Burke specialize in?

    Cardiothoracic Surgery
  • Which character was originally a surgical nurse before becoming a doctor?

    Dr. Ben Warren
  • What is the name of the hospital's resident who is known for being a Muslim woman?

    Dr. Dahlia Qadri
  • Which character has a PhD in Biochemistry?

    Dr. Stephanie Edwards
  • What is the name of the hospital's resident who is known for being a former competitive swimmer?

    Dr. Sam Bello
  • What is the name of the hospital's resident who has a photographic memory?

    Dr. Marissa Harper
  • What is the name of the hospital's resident who is known for being a perfectionist?

    Dr. Stephanie Edwards
  • Which character did Sarah Drew play on Grey's Anatomy?

    Dr. April Kepner
  • What is the name of the hospital's resident who is known for being a transgender man?

    Dr. Casey Parker
  • What is the name of the hospital's resident who is known for being a prodigy?

    Dr. Maggie Pierce
  • Which character did Jessica Capshaw play on Grey's Anatomy?

    Dr. Arizona Robbins
  • What is the name of the hospital's resident who is known for being a former prisoner?

    Dr. Leah Murphy
  • What is the name of the surgical method developed by Dr. Derek Shepherd and Dr. Callie Torres?

    The Shepherd Method
  • Which character did Camilla Luddington play on Grey's Anatomy?

    Dr. Jo Wilson
  • Which character is diagnosed with Alzheimer's disease?

    Dr. Ellis Grey
  • Which character did T.R. Knight play on Grey's Anatomy?

    Dr. George O'Malley
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